منابع مشابه
Catastrophic Kinesins Piecing Together Their Mechanism by 3D Reconstruction
Kin Is, kinesins with an internal catalytic domain, de-polymerize microtubules from both ends, and the KIF2C crystal structure presented by ([this issue of Cell]) provides provocative evidence to support the theory that the highly conserved sequences are critical structural elements in these catastrophic kinesins.
متن کاملMicrotubule-regulating kinesins
How do they reproduce? Unlike many other starfish, the general body surface of crown-of-thorns starfish is soft and flexible, which enables it to swell as it develops huge gonads. Fecundity is obviously related to size, but, as an example, a 40 cm diameter crown-of-thorns starfish may commit about 45% of its total body energy to reproduction and shed an astonishing 50 million eggs. Like many ma...
متن کاملDynamics of heterodimeric kinesins and cooperation of kinesins
Using the model for the processive movement of a dimeric kinesin we proposed before, we study the dynamics of a number of mutant homodimeric and heterodimeric kinesins that were constructed by Kaseda et al. (Kaseda, K., Higuchi, H. & Hirose, K. (2002) PNAS 99, 16058–16063). The theoretical results of ATPase rate per head, moving velocity, and stall force of the motors show good agreement with t...
متن کاملKinesins in cell migration.
Human cells express 45 kinesins, microtubule motors that transport a variety of molecules and organelles within the cell. Many kinesins also modulate the tracks they move on by either bundling or sliding or regulating the dynamic assembly and disassembly of the microtubule polymer. In migrating cells, microtubules control the asymmetry between the front and rear of the cell by differentially re...
متن کاملKinesins at a glance.
Journal of Cell Science 123, 4000 © 2010. Published by The Company of Biologists Ltd doi:10.1242/jcs.082667doi:10. There was an error published in J. Cell Sci. 123, 3420-3423. We misprinted the sentence in the acknowledgements that states the American Heart Association (AHA) as the funding body supporting F. Jon Kull. The correct sentence is given below: The authors’ research on kinesins is sup...
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ژورنال
عنوان ژورنال: Cell
سال: 2004
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(04)00168-0